ISO 17025 ACCREDITED • TORONTO LAB

Comprehensive peptide testing services

Precision HPLC, high-resolution LC-MS/MS, impurity profiling, and more. Every report includes raw data and full method details.

Our full testing capabilities

HPLC Purity Analysis

High-performance liquid chromatography with UV and charged aerosol detection (CAD) for precise determination of peptide purity and related substance profiling. Orthogonal methods available.

Typical turnaround: 3–5 business days • Sample requirement: 1–5 mg
Included in all packages

LC-MS/MS Identity & Sequence Confirmation

High-resolution mass spectrometry for exact mass determination, sequence verification, and detection of modifications, deletions, or impurities. Essential for custom and research peptides.

Typical turnaround: 3–5 business days • Sample requirement: 0.5–2 mg
Included in all packages

Impurity & Related Substances Profiling

Comprehensive identification and quantification of process-related impurities, degradation products, and peptide-related substances using HPLC-UV, CAD, and mass spectrometry.

Typical turnaround: 4–6 business days • Recommended for: IND-enabling or publication data

Residual Solvents & Volatile Impurities (GC-MS)

Gas chromatography-mass spectrometry for residual synthesis solvents and volatile organic compounds according to ICH Q3C guidelines. Critical for research and early clinical peptides.

Typical turnaround: 5 business days • Add-on to Complete/Premium packages

Heavy Metals & Elemental Impurities (ICP-MS)

Inductively coupled plasma mass spectrometry for elemental impurities (Pb, As, Cd, Hg, etc.) per ICH Q3D. Required for peptides used in in vivo or cell-based research.

Typical turnaround: 5–7 business days • Add-on available

Endotoxin Testing (Kinetic Chromogenic LAL)

Bacterial endotoxin quantification using kinetic chromogenic Limulus Amebocyte Lysate (LAL) assay. Essential for any peptide intended for biological research or in vivo studies.

Typical turnaround: 3–5 business days • Premium package add-on

Custom methods & specialized testing available

We develop and validate custom HPLC and mass spec methods for novel sequences, modified peptides, and complex impurity profiles. Contact us to discuss your specific research needs.

Discuss a custom project
STATE-OF-THE-ART EQUIPMENT

Instrumentation you can trust

  • Agilent 1260/1290 Infinity II HPLC systems with UV and CAD detectors
  • Thermo Scientific Orbitrap Exploris 240 high-resolution LC-MS/MS
  • Agilent 8890 GC-MS for residual solvents
  • Agilent 7900 ICP-MS for elemental impurities
  • Validated methods per ICH guidelines
QUALITY & COMPLIANCE
ISO/IEC 17025:2017 accredited (scope includes peptide purity and identity by HPLC and LC-MS)
Full traceability and chain of custody
Raw data, chromatograms, and method validation summaries included with every report
PhD-level review of all results before release
Secure client portal for report access and historical data

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